by Alejandro Speck Planche | Jan 16, 2023 | Pesticides
BACKGROUND: The increasing resistance of several phytopathogenic fungal species to existing agrochemical fungicides has alarmed the worldwide scientific community. In an attempt to overcome this problem, a discriminant model based on substructural descriptors was...
by Alejandro Speck Planche | Jan 16, 2023 | Pesticides
Pesticides represent extremely useful chemical and biochemical agents for the prevention of crop losses and disease in humans. They act by destroying, repelling or mitigating pests. Insects constitute one of the pests which are very difficult to control. With the pass...
by Alejandro Speck Planche | Jan 16, 2023 | Antiparasitics
Artificial neural networks have revolutionized the drug discovery process. Nevertheless, two handicaps associated with this class of machine learning methods still remain: a) their lack of interpretability and b) the inability to simultaneously include several stages...
by Alejandro Speck Planche | Jan 15, 2023 | Antiparasitics
Parasitic diseases remain as unresolved health issues worldwide. While for some parasites the treatments involve drug combinations with serious side effects, for others, chemical therapies are inefficient due to the emergence of drug resistance. This urges the search...
by Alejandro Speck Planche | Jan 15, 2023 | Cancers
Liver cancers are one of the leading fatal diseases among malignant neoplasms. Current chemotherapeutic treatments used to fight these illnesses have become less efficient in terms of both efficacy and safety. Therefore, there is a great need of search for new...
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