by Alejandro Speck Planche | Jan 15, 2023 | Cancers
Background: Cyclin-dependent kinase 4 (CDK4) and the human epidermal growth factor receptor 2 (HER2) are two of the most promising targets in oncology research. Thus, a series of computational approaches have been applied to the search for more potent inhibitors of...
by Alejandro Speck Planche | Jan 14, 2023 | Cancers
Respiratory viruses are infectious agents, which can cause pandemics. Although nowadays the danger associated with respiratory viruses continues to be evidenced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the virus responsible for the...
by Alejandro Speck Planche | Jan 12, 2023 | Antivirals
Human immunodeficiency virus (HIV) is responsible for causing the life-threatening condition known as acquired immune deficiency syndrome (AIDS). Current antiretroviral regimens are usually effective in halting the progression of HIV/AIDS, but serious concerns exist...
by Alejandro Speck Planche | Jan 11, 2023 | Antivirals
Hepatitis C constitutes an unresolved global health problem. This infectious disease is caused by the hepatotropic hepatitis C virus (HCV), and it can lead to the occurrence of life-threatening medical conditions, such as cirrhosis and liver cancer. Nowadays, major...
by Alejandro Speck Planche | Jan 10, 2023 | Antivirals
Multi-Condition QSAR Model for the Virtual Design of Chemicals with Dual Pan-Antiviral and Anti-Cytokine Storm Profiles Respiratory viruses are infectious agents, which can cause pandemics. Although nowadays the danger associated with respiratory viruses continues to...
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